An enzyme without its cofactor is termed an apoenzyme.

没有辅助因子叫做脱辅。

Some holoenzymes, such as pyruvate dehydrogenase, are highly compex, with several cofactors.

有一些全是高度复杂，如丙酮酸脱。

A cofactor bound loosely to the apoenzyme and readily separable from it is a coenzyme.

脱辅基蛋白结松弛、易于之辅基因子称为辅。

When a catalytically active enzyme forms a complex with a cofactor a holoenzyme is produced.

蛋白和辅助因子两者结成完整子时，形成具有活力全。

Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.

甲基丙二酸血症是由于甲基丙二酰辅A变位或其辅腺苷钴胺素缺陷所致一种遗传性代谢疾病。