congenital defect

He has a congenital heart defect.

他有先天性心脏。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变一种，无论有无接受胰岛素治疗，先天畸形仍可能形成。

This was true whether applied to a congenital defect, such as syndactyly, or an acquired defect, such as a burn contracture.

把它们应用于诸如先天损或是烧伤疤痕挛缩类后天损修复，往往都没错。