Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).
摘要转酮醇
是磷酸戊糖途径
关键
,催化二碳单元在酮糖(供体)和醛糖(受体)间
转移。
Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).
摘要转酮醇
是磷酸戊糖途径
关键
,催化二碳单元在酮糖(供体)和醛糖(受体)间
转移。
The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.
对醛搪还原
抑制剂依帕司他
合成工艺作了改进,使中间体绕

酸
收率提高到76.4%。
Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.
哒嗪酮类化合物具有多种重要
生物活性,根据作用机制
不同,可分为钙增敏剂、磷酸二酯
抑制剂、环氧合
抑制剂等,并可用于相关疾病
治疗。
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